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Education Employment Publications Activities Skills

 

Scientific papers

Scientific abstracts

Posters

Oral presentations

The Second AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development: Maximizing Opportunities for Individualized Treatment, Atlanta, GA, USA
17/09/2007 - 20/09/2007
"Base5, a versatile, highly integrated high-throughput methylation profiling platform for Methylation-Specific PCR based marker identification applied to CRC [pdf poster not yet availanble]
Josef Straub, Geert Trooskens, Katja Bierau, Joost Louwagie, and Wim van Criekinge

The Second AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development: Maximizing Opportunities for Individualized Treatment, Atlanta, GA, USA
17/09/2007 - 20/09/2007
"Correlation between testing MGMT gene promoter methylation status of glioblastoma tissue using nested gel-based and direct real-time fluorescence-based Methylation-Specific PCR" [pdf poster not yet availanble]
Ilse Vlassenbroeck, Stéphane Califice, Annie-Claire Diserens, Eugenia Migliavacca, Josef Straub, Ivano Di Stefano, Fabrice Moreau, Marie-France Hamou, Isabelle Renard, Mauro Delorenzi, Bruno Flamion, Katja Bierau, and Monika E. Hegi

The Second AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development: Maximizing Opportunities for Individualized Treatment, Atlanta, GA, USA
17/09/2007 - 20/09/2007
"Feasibility of a DNA methylation-based assay for non-invasive CRC screening using stool" [pdf poster not yet availanble]
Joost Louwagie, Linda Bosch, Sandra van den Bosch, Mark Opdam, Josef Straub, Gaetan Otto, Wim van Criekinge, Madeleine Grooteclaes, Jochim Terhaar sive Droste, Beatriz Carvalho, Reinhold Stockbrugger, Gerrit Meijer, Manon van Engeland, Maarten Penning, Katja Bierau, and Adriaan de Bruine

The Second AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development: Maximizing Opportunities for Individualized Treatment, Atlanta, GA, USA
17/09/2007 - 20/09/2007
"Feasibility of a urine-based DNA methylation assay for early detection of bladder cancer" [pdf poster not yet availanble]

Isabelle Renard, John Kelly, Catherine Collette, Christophe Naômé, Hubert Nicolas, Ellen Zwarthoff, Josef Straub, Wim Van Criekinge, Lokesh Suraparaju, Katja Bierau, and David Waltregny

MGMT Conference, Mainz, Germany
13/06/2007 - 16/06/2007
"A new method for testing MGMT gene promoter methylation status of glioblastoma tissue using a direct real-time fluorescence-based methylation-specific PCR" [pdf poster not yet available]
Stéphane Califice, Annie-Claire Diserens, Ilse Vlassenbroeck, Eugenia Migliavacca, Josef Straub, Ivano Di Stefano, Fabrice Moreau, Marie-France Hamou, Isabelle Renard, Mauro Delorenzi, Katja Bierau, Monika E. Hegi

98th Annual Meeting AACR, Los Angeles, CA, USA
14/04/2007 - 18/04/2007
"A non-invasive urine-based research test for the detection of prostate cancer using DNA methylation" [pdf poster not yet available]
Tatiana I. Vener, Carlo Derecho, Shobha Varde, Abhijit Mazumder, Madeleine Grooteclaes, Katja Bierau, Joost Louwagie, Joseph Bigley, Laurence De Leval, Jean De Leval, Yves Gaspar, Luc Coppens, David Waltregny

Modern Drug Discovery & Development Summit, Philadelphia, PA, USA
04/12/2006 - 06/12/2006
"MGMT methylation testing as a Pharmacogenomic Biomarker in a large international clinical Glioma Treatment trial" [pdf poster not yet available]
Bigley, J., Bierau, K., Hegi, M., Diserens, A.-C., Mehta, M., Aldape, K., Berkey, B., and Gilbert, M.

The First AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development: Maximizing Opportunities for Individualized Treatment, Chicago, Illinois, USA
12/09/2006 - 15/09/2006
"Pharmacomethylomics: methylation profiling applied to drug resistance models" [pdf poster click here]

J. Straub, P. de Graef, G. Trooskens, K. Bierau, S. de Jong, J. W. Bigley, A. van der Zee, H. Spolders, W. M. Van Criekinge

97th Annual Meeting AACR, Washington, DC, USA
01/04/2006 - 05/04/2006
"O6-Alkylguanine-DNA Alkyltransferase (AGT) and microsatellite instability (MSI) analyses in malignant glioma" [pdf poster not available]
Jill A. Maxwell, Stewart P. Johnson, Roger E. McLendon, Francis Ali-Osman, Jennifer A. Quinn, Allan H. Friedman, James E. Herndon, Katja Bierau, Joseph Bigley, Darell D. Bigner & Henry S. Friedmann

ASCO Prostate Cancer Symposium, San Fransico, CA, USA
24/02/2006 - 26/02/2006
"Development of a multiplexed DNA methylation assay for prostate cancer detection" [pdf poster click here]
S. Varde, J. Louwagie, K. Bierau, J. Bigley, J. Mehrotra, T.Vener, H. Chiu, C. Derecho &A. Mazumder

O6-Alkylguanine-DNA Alkyltransferase ", Keele, UK
06/08/2005 - 09/08/2005
"Comparison of gel-based MSP and real-time fluorescence-based MSP to determine the methylation status of the MGMT gene promoter in glioblastoma samples" [pdf poster click here]
Stéphane Califice, Annie-Claire Diserens, Ivano Di Stefano, Fabrice Moreau, Ellen Klaver, Isabelle Renard, Monika E. Hegi & Katja Bierau

AACR - Chromatin, Chromosomes & Cancer Epigenetics, Waikoloa, Hawaii
10/11/2004 - 14/11/2004
"Molecular separation of benign prostate hyperplasia (BPH) and adenocarcinoma of the prostate (PCa) using a robust and specific MSP-based assay for the GST-Pi gene" [pdf poster click here]
Vlassenbroeck, I., Penning, M., Klaver, E., Bigley, J. & Bierau, K.

3rd Scientific Symposium, Pamgene, s'-Hertogenbosch, The Netherlands
15/12/2003
"Prediction of toxic side effects during drug development exemplified on necrosis and inflammation processes in rat livers"
[pdf poster click here]
Vlassenbroeck, I., Straub, J., Chan, A. & Bierau, K.

TIGR's 15th Annual Genome Sequencing and Analysis Conference (GSAC XV), September 21-24, 2003, Savannah International Trade and Convention Center, Savannah, Georgia; Van Beuningen, R., Schmeiser, K., Vlassenbroeck, I., Thorburn, R., Naji, F., Wu, Y. & Chan, A. (2003), Development of a New 96-Well Microplate High Throughput Micorarray Analysis System for Expression Profiling using PamChip Arrays. [pdf abstract click here]

EuroTox - New Horizons in Toxicology for a Safer Future, Istanbul, Turkey
13/09/2001 - 16/09/2001
"New molecular tools for predictive toxicology: The role of molecular databases and comprehensive microarrays" [pdf poster click here, pdf abstract click here]
Alen, P., Schmeiser, K., Whitford, W., Hicken, S. & Farris, G.

EuroTox - New Horizons in Toxicology for a Safer Future, Istanbul, Turkey
13/09/2001 - 16/09/2001
"Differential gene expression in rats after injection with kidney toxicants" [pdf abstract click here]
Schmeiser, K., Alen, P., Farris, G. & Kier, L.

EuroTox - New Horizons in Toxicology for a Safer Future, Istanbul, Turkey
13/09/2001 - 16/09/2001
"Toxicogenomic approach to predicting adverse drug responses" [pdf poster click here, pdf abstract click here]
Alen, P., Schmeiser, K., Jongedijk, E. & Neft, R. E.

31st Annual Meeting of the European Environmental Mutagen Society, Ghent, Belgium
01/09/2001 - 05/09/2001
'Differential gene expression in rats after injection with kidney toxicants" [pdf abstract click here]
Schmeiser, K., Alen, P., Farris, G. & Kier, L.

31st Annual Meeting of the European Environmental Mutagen Society, Ghent, Belgium
01/09/2001 - 05/09/2001
"New molecular tools for predictive toxicology: The role of molecular databases and comprehensive microarrays" [pdf poster click here, pdf abstract click here]
Alen, P., Schmeiser, K., Whitford, W., Hicken, S. & Farris, G.

EuroBiochips, Munich, Germany
05/06/2001 - 08/06/2001
"Toxicogenomic approach to predicting adverse drug responses" [pdf poster click here, pdf abstract click here]
Alen, P., Schmeiser, K., Jongedijk, E. & Neft, R. E.

EuroBiochips, Munich, Germany
05/06/2001 - 08/06/2001
"New molecular tools for predictive toxicology: The role of molecular databases and comprehensive microarrays" [pdf poster click here, pdf abstract click here]
Alen, P., Schmeiser, K., Whitford, W., Hicken, S. & Farris, G.

In vitro models and toxicity mechanisms, Verona, Italy
30/05/2001 - 01/06/2001
"Individual risk assessment: the use of toxicogenomics to predict adverse drug responses" [pdf poster click here, pdf abstract click here]
Schmeiser, K., Neft, R. E., Adair, K., Snyman, H. & Farr, S. B.

DTT Europe, Stuttgart, Germany
23/04/2001 - 26/04/2001
"Differential gene expression in rats after injection with kidney toxicants" [pdf abstract click here]
Schmeiser, K., Alen, P., Farris, G. & Kier, L.

DTT Europe, Stuttgart, Germany
23/04/2001 - 26/04/2001
"Toxicogenomic approach to predicting adverse drug responses" [pdf poster click here, pdf abstract click here]
Alen, P., Schmeiser, K., Jongedijk, E. & Neft, R.E.

SOT (40th annual meeting) Society of Toxicology, San Fransisco, CA, USA
25/03/2001 - 29/03/2001
"Gene expression profiling and pattern comparison from rat liver and primary hepatocytes after treatment with Chlorpromazine" [pdf poster click here, pdf abstract click here]
Kalkuhl, A., Dunn, R. T., Krebsfaenger, N., Bader, R., Farris, G., Schmeiser, K., Field, A., Tian, X., Snyman, H., Farr, S. B. & Singer, T

Postgraduate Research Day, University of Birmingham, UK
November 1999
"Multiplicity of apoptosis specific proteins (ASPs) expressed from the Apg5L gene: evidence for a link between apoptosis and autophagy"
Schmeiser, K., Rooks, S., Burnett, C., Hammond, E. M. & Grand, R. J. A.

Programmed Cell Death, Cold Spring Habor, USA
October 1999
"Characterization of apoptosis specific proteins (ASPs) as cytoskeletal components"
Schmeiser, K., Burnett, C. & Grand, R. J. A.

Postgraduate Research Day, University of Birmingham, UK
November 1998
"Specific cleavage of gamma catenin by caspases during apoptosis"
Schmeiser, K., Hammond, E. M. & Grand, R. J. A.

Epithelial Cell Science, Oxford, UK
September 1998
"Cleavage of adherent junction proteins by caspases during apoptosis"
Schmeiser, K., Hammond, E. M. & Grand, R. J. A.